Xuexiang Han

( 韩雪祥 )

Principal Investigator

xuexiang.han@sibcb.ac.cn

Xuexiang Han received a B.E. in Chemical Engineering from Shanghai University in 2014 and a Ph.D. in Chemistry from Tsinghua University (a joint PhD program with National Center for Nanoscience and Technology) in 2019 under the supervision of Profs. Yuliang Zhao (赵宇亮), Yadong Li (李亚栋) and Guangjun Nie (聂广军). He was a Postdoctoral Fellow in Prof. Michael J. Mitchell's lab in the Department of Bioengineering at University of Pennsylvania during 2020–2024. In Feb 2024, Dr. Han joined Center for Excellence in Molecular Cell Science (i.e., Shanghai Institute of Biochemistry and Cell Biology), Chinese Academy of Sciences (CAS) as a Professor/Principal Investigator. The Han Lab focuses on novel lipid nanoparticles (LNPs) for RNA vaccines/therapeutics development to address the unmet biomedical needs. Dr. Han has published 60+ papers in peer-reviewed journals, including Nature, Nat. Chem., Nat. Nanotechnol., Nat. Biomed. Eng., Nat. Mater., Nat. Commun., JACS etc.

Staff

Haibo Song

( 宋海波 )

Lab manager

songhaibo@sibcb.ac.cn

Jie Yang

( 杨捷 )

Associate Investigator

jie.yang@sibcb.ac.cn

LNP for immunotherapy

Xuehe Lu

( 卢学和 )

Assistant Investigator

luxuehe@sibcb.ac.cn

Lipid and nucleic acid chemistry

Miaomiao Sun

( 孙苗苗 )

Technician

sunmiaomiao@sibcb.ac.cn

Guangyan Huang

( 黄广燕 )

Technician

huangguangyan@sibcb.ac.cn

Bowen Wu

( 吴博文 )

Postdoc

wubowen@sibcb.ac.cn

LNP development and application

Student

Nei Li

( 李内 )

Graduate Student

linei2023@sibcb.ac.cn

LNP for therapeutic RNA delivery

Fan Wu

( 吴凡 )

Graduate Student

wufan2023@sibcb.ac.cn

mRNA-LNP for genome editing

Yudian Xiao

( 肖雨点 )

Graduate Student

xiaoyudian2023@sibcb.ac.cn

mRNA-LNP for immunotherapy

Yijia Hao

( 郝怡嘉 )

Graduate Student

haoyijia2023@sibcb.ac.cn

Cancer mRNA vaccine

Fenglin Song

( 宋凤麟 )

Graduate Student

songfenglin2024@sibcb.ac.cn

LNP-based protein replacement therapy

Sijia Xu

( 许思嘉 )

Graduate Student

xusijia2024@sibcb.ac.cn

LNP-based immunotherapy

Zhenzhen Hu

( 胡真真 )

Graduate Student

huzhenzhen2024@sibcb.ac.cn

LNP for targeted delivery

Alumni

Yun Zeng/曾云 (2024.7–2025.06, Technician; Now: TBD)

Yining Yao/姚怡宁 (2025.02–2025.04, Intern; Now: TBD)

Chenxing Yan/严晨星 (2024.11–2025.04, Intern; Now: TBD)

Siying Long/龙思颖 (2024.11–2025.04, Intern; Now: TBD)

Zhiyi Xiong/熊志怡 (2024.07–2024.08, Rotation Student; Now: Graduate Student, CEMCS)