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  2. Huang PW#, Gao WN#, Fu CY#, Wang M#, Li YG#, Chu BZ, He A, Li Y, Deng XM, Zhang YH, Kong Q, Yuan JX, Wang HB, Shi Y*, Gao D*, Qin RY*, Hunter T, Tian RJ*. Clinical functional proteomics of intercellular signalling in pancreatic cancer. Nature. 2024 Nov 13. doi: 10.1038/s41586-024-08225-y. (PubMed Link)
  3. Guo WX#, Zhang XY#, Li L#, Shao PF#, Liang C#, Zhang HJ, Wang SM, Peng YY, Liu K, Luo J, Ju Y, DeMarzo AM*, Yu C*, Chen LN*, Zhou B*, Gao D*. JAK/STAT signaling maintains intermediate cell population in prostate basal cell fates determination. Nat Genet. 2024 Dec;56(12):2776-2789. (PubMed Link)
  4. Li F#, Dai PF#, Shi HL#, Zhang YJ#, He J, Gopalan A, Li D, Chen Y, Du YR, Xu GL, Yang WW*, Liang C*, Gao D*. LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer. Cell Res. 2025 Jan;35(1):59-71. Research highlights by Shaghayegh Nouruzi & Amina Zoubeidi, Cell Res. 2025 Jan;35(1):5-6. (PubMed Link)
  5. Han M#, Li F#,*, Zhang YH#, Dai PF, He J, Li YG, Zhu YQ, Zheng JK, Huang H, Bai F, Gao D*. Foxa2 drives lineage plasticity and Kit pathway activation in neuroendocrine prostate cancer. Cancer Cell. 2022 Nov 14;40(11):1306-1323.e8. Preview by Azad AA, Kostos L and Agarwal N, Cancer Cell, 2022 40:1266-1268; Research highlights by Maria Chiara Masone, Nat Rev Urol, 2023 Jan;20(1):8; Cancer Discovery  2022 Nov 18:OF1. (PubMed Link)
  6. Guo WX, Li L, He J, Liu Z, Han M, Li F, Xia XY, Zhang XY, Zhu Y, Wei Y, Li YG, Aji R, Dai H, Wei H, Li CF, Chen Y*, Chen LN*, Gao D*. Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips. Nature Genetics. 2020 Sep;52(9):908-918. (PubMed Link)
  7. Tang D, Wang HX, Huang XZ, Li F, Zhu H, Li Y, He LJ, Zhang H, Pu WJ, Liu K, Zhao H, Bentzon JF, Yu Y, Ji Y, Nie Y, Zhang L*, Gao D*, Zhou B*. Sca1+ Vascular Stem Cells Contribute to Smooth Muscle for Artery Repair and Regeneration. Cell Stem Cell. 2020 Jan 2;26(1):81-96. (PubMed Link)
  8. Gao D, Vela I, Sboner A, Iaquinta PJ, Karthaus WL, Gopalan A, Wanjala JN, Dowling C, Undvall EA, Wongvipat J, Kossai M, Barboza LP, Di W, Cao Z, Zhang QF, Sirota I, Ran Ll, Solomon SB, MacDonald TY, Beltran H, Mosquera J,  Eastham JA, Touijer KA, Scardino PT, Laudone VP, Rathkopf DE, Morris MJ, Danila DC, Slovin SF, Chi P, Clevers H, Carver B, Rubin MA, Scher HI, Sawyers CL, Chen Y. Generation of in vitro organoids cultures derived from patients with advanced prostate cancer. Cell. 2014 Sep; 159: 176-187. (PubMed Link)
    2025     
  1. Yin XY#, Shen H#, Wang H#, Wang QC#, Zhang S#, Zhang CM, Jia Q, Guo SW, Xu XF, Zhang WH, Li B, Shi XH, Gao SZ, Shi ML, Zhao XN, Wang S, Han JW, Zhang GX, Li YK, Li PH, Jing W, Song B, Zheng KL, Li G, Zhang YJ, Jiang H, Wu C, Song ZJ, Niu G, Zhang QZ, Guo JL, Sun Z, Han FX, Li YG, Gao D, Jin HJ*, Yang HB*, Li J*, Jin G*. Pathogenic Germline Variants in Chinese Pancreatic Adenocarcinoma Patients. Nat Commun. (AIP)
  2. Wang NT#, Pachai MR#, Li D#, Lee C, Warda S, Khudoynazarova MN, Xie GJ, Sagar SR, Li Y, Qian C, Wong EW, Yan J, Tomas FV, Hu WH, Kuo FS, Gao SZ, Luo JQ, Smith A, Han M, Gao D, Ge K, Yu HY, Chandarlapaty S, Iyer GV, Rosenberg JE, Solit DB, Al-Ahmadie HA, Chi P*, Chen Yu*.  Loss of Kmt2c or Kmt2d primes urothelium for tumorigenesis and redistributes KMT2A-menin to bivalent promoters. Nat Genet. 2025 Jan 13. doi: 10.1038/s41588-024-02015-y. (PubMed Link)
  3. Li F#, Dai PF#, Shi HL#, Zhang YJ#, He J, Gopalan A, Li D, Chen Y, Du YR, Xu GL, Yang WW*, Liang C*, Gao D*. LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer. Cell Res. 2025 Jan;35(1):59-71. (PubMed Link)
    4. 2024    
  4. Guo WX#, Zhang XY#, Li L#, Shao PF#, Liang C#, Zhang HJ, Wang SM, Peng YY, Liu K, Luo J, Ju Y, DeMarzo AM*, Yu C*, Chen LN*, Zhou B*, Gao D*. JAK/STAT signaling maintains intermediate cell population in prostate basal cell fates determination. Nat Genet. 2024 Dec;56(12):2776-2789. (PubMed Link)
  5. Huang PW#, Gao WN#, Fu CY#, Wang M#, Li YG#, Chu BZ, He A, Li Y, Deng XM, Zhang YH, Kong Q, Yuan JX, Wang HB, Shi Y*, Gao D*, Qin RY*, Hunter T, Tian RJ*. Clinical functional proteomics of intercellular signalling in pancreatic cancer. Nature. 2024 Nov 13. doi: 10.1038/s41586-024-08225-y. (PubMed Link)
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  7. Zhang XY#, Wang J#, Guo WX*, Zhang HJ, Zhou B, Chen Y, Gao D*. The cell fates of intermediate cell population in prostate development. Cell Insight. 2024 Jul 4;3(4):100182. (PubMed Link)
  8. Li F#, Xing XD#, Jin QQ#, Wang XM#, Dai PF#, Han M#, Shi HL, Zhang Z, Shao XL, Peng YY, Zhu YQ, Xu JY, Li D, Chen Y, Wu W, Wang Q, Yu C*, Chen LN*, Bai F*, Gao D*. Sex differences orchestrated by androgens at single-cell resolution. Nature. 2024 May;629(8010):193-200. (PubMed Link)
  9. Tong XY#, Patel AS#, Kim E#, Li HJ#, Chen YQ, Li S, Liu SW, Dilly J, Kapner KS, Xue Y, Hover L, Mukhopadhyay S, Sherman F, Mynzdar K, Gao YJ, Li F, Li FM, Fang ZY, Jin YJ, Gao JT, Shi ML, Chen LN, Chen Y, Kheoh T, Yang WJ, Yanai I, Moriera AL, Velcheti V, Neel BG, Hu L, Christensen JG, Olson P, Gao D, Zhang MQ*, Aguirre AJ*, Wong KK*, Ji HB*. Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer. Cancer Cell. 2024 Feb 20:S1535-6108(24)00036-9. (PubMed Link)
  10. Chen L#,*, Zhang C#, Xue RD#, Liu M#, Bai J#, Bao JX#, Wang Y#, Jiang NH, Li ZX, Wang WW, Wang RR, Zheng B, Yang AR, Hu J, Liu K, Shen SY, Wang YQ, Zhu YJ, Yang S, Gao Q, Gu J, Gao D, Wang XW, Nakagawa H, Zhang N, Wu L*, Rozen SG*, Bai F*, Wang HY*. Deep Whole Genome Analysis of 494 Hepatocellular Carcinomas. Nature. 2024 Feb 14.  doi: 10.1038/s41586-024-07054-3. (PubMed Link)
  11. Zhu YJ#, Tang SJ#, Yuan QY#, Fu J#, He J#, Liu Z, Zhao XF, Li YG, Zhao Y, Zhang YN, Zhang XY, Zhang YQ, Zhu YQ, Wang WW, Zheng B, Wu R, Wu T, Yang S, Qiu XY, Shen SY, Hu J, Chen LN*, Wang Y, Wang HY*, Gao D*, Chen L*. Integrated characterization of hepatobiliary tumor organoids provides potential landscape of pharmacogenomic interactions. Cell Rep Med. 2024 Jan 17:101375. (PubMed Link)
    12. 2023     
  12. Li YG#, Tang SJ#, Shi XH#, Lv JW#, Wu XY#, Zhang YH#, Wang H, He J, Zhu YQ, Ju Y, Guo SW, Yang WW*, Yin HY*, Chen LN*, Gao D*, Jin G*. Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant pancreatic cancer. Cell Rep Med. 2023 Sep 19;4(9):101162.  (PubMed Link)
  13. Li X#, Li F#, Ye F#, Guo HT, Chen WT, Jin J, Wang YR, Dai PF, Shi HL, Tao HR, Dang WZ, Ding YL, Wang MC, Jiang HL, Chen KX, Zhang NX, Gao D*, Zhang YY*, Luo C*. Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer. Cell Rep. 2023 Jul 14;42(7):112798. (PubMed Link)
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    16. 2022    
  16. Li L#, Xu YL#, Yan LL#, Li X, Li F, Liu Z, Zhang CC, Yuan L*, Gao D*, Cheng X*, Chen LN*.  Dynamic network biomarker factors orchestrate cell-fate determination at tipping points during hESC differentiation. Innovation (Camb). 2022 Dec 20;4(1):100364. (PubMed Link)
  17. He J#, Cui HY#, Shi XH, Jin QQ, Han XM, Han TT, Peng JY, Guo SW, Zhao Y, Zhou B, Chen LN, Chen L, Zeng YA, Wang HY*, Jin G*, Gao D*. Functional hepatobiliary organoids recapitulate liver development and reveal essential drivers of hepatobiliary cell fate determination. Life Medicine. 2022 Dec 07;lnac055. (Paper Link)
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    28. 2021     
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    35. 2020     
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