Home CAS Center for Excellence


Members of CAS, CAE
National Outstanding Young Scientists Award
Principal Investigators
Address: 320 Yue Yang Road, Shanghai 200031, P.R. China
Tel: 86-21-54920000
Fax: 86-21-54921011
Email: sibcb@sibs.ac.cn
Website: www.sibcb.ac.cn
Principal Investigators
ZHANG Youshang
Ph.D., Professor
Member of CAS, Editor-in-Chief of "Acta Biochem Biophys Sin"
Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue-yang Road, Shanghai 200031, China.
Email: yszhang@@sibcb.ac.cn

Research Areas
bovine and human insulin expression, purification and crystallization

Education Background & Academic Experience
Zhang Youshang, male, Han nationality, is a native of Changsha, Hunan Province. He graduated from Zhejiang University in 1948 and received a postgraduate degree from the Shanghai Biochemistry Research Institute of the Chinese Academy of Sciences in 1961. Zhang Youshang has long been engaged in the research of protein structure and function. He separated purified crystal re-synthesized insulin from coarse products and showed that re-synthesized modules had a three dimensional structure of natural insulin modules. Zhang also synthesized crystal insulin active pieces using an enzyme promotion method. He established a new technique to produce pig insulin and researched the modular evolution of insulin and realized the high expression of re-combined human insulin in yeast cells. He also researched the protein project of insulin. Zhang synthesized an epidermis growth factor analog using an enzyme promotion method. He researched the crystal structure of tobacco mosaic disease albumen sub-base. Zhang is an academician of the Chinese Academy of Sciences.


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