国家蛋白质科学
中心•上海(筹)

分子生物学国
家重点实验室

细胞生物学国
家重点实验室

上海市分子男
科学重点实验室

中科院系统生物学
重点实验室
 

科学研究

研究领域
科研项目
科研成果
  • 代表性论文
• 历年发表论文
• 获奖成果
• 授权专利
• 新药证书
研究开发
 
 
地址:上海市岳阳路320号
邮编:200031
电话:86-21-54920000
传真:86-21-54921011
邮箱:sibcb@sibcb.ac.cn

科研成果 > 代表性论文

 

2017

  1. Mingliang Jin,Yao Cong. Identification of an allosteric network that influences assembly and function of group II chaperonins. Nat Struct Mol Biol. (2017)24:683-684.
  2. Min Shi,Heng Zhang,Xudong Wu,Zhisong He,Lantian Wang,Shanye Yin,Bin Tian,Guohui Li,Hong Cheng. ALYREF mainly binds to the 5΄ and the 3΄ regions of the mRNA in vivo. Nucleic Acids Res. (2017)
  3. Hui Zhang,Xiuzhen Huang,Kuo Liu,Juan Tang,Lingjuan He,Wenjuan Pu,Qiaozhen Liu,Yan Li,Xueying Tian,Yue Wang,Libo Zhang,Ying Yu,Hongyan Wang,Ronggui Hu,Fengchao Wang,Ting Chen,Qingdong Wang,Zengyong Qiao,Li Zhang,Kathy O Lui,Bin Zhou. Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium. Cell Res. (2017)
  4. Jing Fan,Bin Kuai,Guifen Wu,Xudong Wu,Binkai Chi,Lantian Wang,Ke Wang,Zhubing Shi,Heng Zhang,She Chen, Zhisong He,Siyuan Wang,Zhaocai Zhou,Guohui Li,Hong Cheng. Exosome cofactor hMTR4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export. EMBO J. (2017)
  5. Hongli Hu,Daming Gao. PCAF and SIRT7 modulate PGK1 K323 acetylation in liver cancer cells. Hepatology (2017)
  6. Yuhong Han,Yue Xiong,Xuanming Shi,Jiang Wu,Yun Zhao,Jin Jiang. Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system. PLoS Biol. (2017)
  7. Xueying Tian,Yan Li,Lingjuan He,Hui Zhang,Xiuzhen Huang,Qiaozhen Liu,Wenjuan Pu,Libo Zhang,Yi Li,Huan Zhao,Zhifu Wang,Jianhong Zhu,Yu Nie,Shengshou Hu,David Sedmera,Tao P.Zhong,Ying Yu,Li Zhang,Yan Yan,Zengyong Qiao,Qingdong Wang,Sean M.Wu,William T.Pu, Robert H.Anderson,Bin Zhou. Identification of a hybrid myocardial zone in the mammalian heart after birth. Nat Commun.(2017)8,87.
  8. Bo O.Zhou,Hua Yu,Rui Yue,Zhiyu Zhao,Jonathan J.Rios,Olaia Naveiras,Sean J. Morrison. Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF. Nat Cell Biol. (2017)
  9. Ludi Zhang,Lijian Hui. Bioengineering: Bile ducts regenerated. Nature (2017)547:171-172.
  10. Lingjuan He,and Bin Zhou.Cardiomyocyte proliferation: remove brakes and push accelerators. Cell Res.(2017)
  11. Lunyi Li,Xingdong Guo,Xiaoshan Shi,Changting Li,Wei Wu,Chengsong Yan,Haopeng Wang,Hua Li,Chenqi Xu. Ionic CD3−Lck interaction regulates the initiation of T-cell receptor signaling. Proc Natl Acad Sci USA. (2017)
  12. Lingjuan He,Xiuzhen Huang,Onur Kanisicak,Yi Li,Yue Wang,Yan Li,Wenjuan Pu,Qiaozhen Liu,Hui Zhang,Xueying Tian,Huan Zhao,Xiuxiu Liu,Shaohua Zhang,Yu Nie,Shengshou Hu,Xiang Miao,Qingdong Wang,Fengchao Wang,Ting Chen,Qingbo Xu,Kathy O.Lui,Jeffery D.Molkentin,Bin Zhou. Preexisting endothelial cells mediate cardiac neovascularization after injury. J Clin Invest. (2017)
  13. Huang Wu,Li Yang,Lingling Chen. The Diversity of Long Noncoding RNAs and Their Generation. Trends Genet. (2017)
  14. Xiang Li,Chuxiao Liu,Wei Xue,Yang Zhang,Shan Jiang,Qingfei Yin,Jia Wei,Runwen Yao,Li Yang,and Lingling Chen. Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection. Mol Cell.(2017)67,214-227. Commentary , Meet the Author.
  15. Nan Qi,Yuheng Shi,Rui Zhang,Wenting Zhu,Bofeng Yuan,Xiaoyan Li,Changwan Wang,Xuewu Zhang,Fajian Hou. Multiple truncated isoforms of MAVS prevent its spontaneous aggregation in antiviral innate immune signalling. Nat Commun. (2017)138:15676.
  16. Yongjian Wang,Yan Bian,Jie Luo,Ming Lu,Ying Xiong,Shuyuan Guo,Huiyong Yin,Xu Lin,Qin Li,Catherine C.Y. Chang,Tayuan Chang,Boliang Li,and Baoliang Song. Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation. Nat Cell Biol. (2017)
  17. Quanquan Ji,Zhipeng Fang,Qing Ye,Chengwu Chi,Enduo Wang. Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain. Nucleic Acids Res. (2017)
  18. Lantao Gou,Junyan Kang,Peng Dai,Xin Wang,Feng Li,Shuang Zhao,Man Zhang,Minmin Hua,Yi Lu,Yong Zhu,Zheng Li,Hong Chen,Ligang Wu,Dangsheng Li,Xiangdong Fu,Jinsong Li,Huijuan Shi,and Mofang Liu. Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis. Cell (2017)
  19. Hong Peng, Jiao Yang, Guangyi Li, Qing You, Wen Han, Tianrang Li, Daming Gao, Xiaoduo Xie, Byunghoon Lee, Juan Du, Jian Hou, Tao Zhang, Hai Rao, Ying Huang, Qinrun Li, Rong Zeng, Lijian Hui, Hongyan Wang, Qin Xia, Xuemin Zhang, Yongning He, Masaaki Komatsu, Ivan Dikic, Daniel Finley, Ronggui Hu. Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress. Cell Res. (2017)27:657-674.Commentary.
  20. Rujuan Liu,Tao Long,Jing Li,Hao Li,Enduo Wang. Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6. Nucleic Acids Res. (2017)
  21. Yuhang Xing,Runwen Yao,Yang Zhang,Chunjie Guo,Shan Jiang,Guang Xu,Rui Dong,Li Yang,Lingling Chen. SLERT Regulates DDx21 Rings Associated with Pol I Transcription. Cell (2017)169, 664–678.
  22. Yuheng Shi, Bofeng Yuan, Wenting Zhu, Rui Zhang1, Lin Li, Xiaojing Hao, She Chen, Fajian Hou. Ube2D3 and Ube2N are essential for RIG-I-mediated MAVS aggregation inantiviral innate immunity. Nat Commun. (2017)
  23. Lingbo Wang, Minyin Li, Chao Qu, Wanying Miao, Qi Yin, Jiaoyang Liao, Huateng Cao,Min Huang, Kai Wang, Erwei Zuo, Guangdun Peng, Shuxin Zhang, Guodong Chen, Qing Li, Ke Tang,Qian Yu, Zhoujie Li, Catherine CL Wong, Guoliang Xu, Naihe Jing, Xiang Yu, Jinsong Li. CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development. Cell Res. (2017)
  24. Keliang Wu, Cuiqing Zhong, Tailai Chen, Xiaoyu Zhang, Wenrong Tao, Jingye Zhang, Hongchang Li, Han Zhao, Jinsong Li,Zijiang Chen. Polar bodies are efficient donors for reconstruction of human embryos for potential mitochondrial replacement therapy. Cell Res. (2017)
  25. Qiaoshi Lian, Jun Xu, Shanshan Yan, Min Huang, Honghua Ding, Xiaoyu Sun, Aiwei Bi, Jian Ding, Bing Sun, Meiyu Geng. Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation. Cell Res. (2017)
  26. Xingdong Guo, Chengsong Yan, Hua Li, Wenmao Huang, Xiaoshan Shi, Min Huang, Yingfang Wang, Weiling Pan, Mingjun Cai, Lunyi Li, Wei Wu, Yibing Bai, Chi Zhang, Zhijun Liu, Xinyan Wang, Xiaohui F Zhang, Chun Tang, Hongda Wang, Wanli Liu, Bo Ouyang, Catherine C Wong, Yi Cao,Chenqi Xu. Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor. Cell Res. (2017)27:505–525.
  27. Cong Chen, Peili Gu, Jian Wu, Xianyun Chen, Shuangshuang Niu, Hong Sun, Lijie Wu, Na Li, Junhui Peng, Shaohua Shi, Cuiying Fan, Min Huang, Catherine C.L.Wong, Qingguo Gong, Chandan Kumar-Sinha, Rongguang Zhang, Lajos Pusztai, Rekha Rai, Sandy Chang, Ming Lei. Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer. Nat Commun. (2017)
  28. Ye Tao,Chen Zhong,Junjun Zhu,Shutong Xu,Jianping Ding. Structural and mechanistic insights into regulation of HBO1 histone acetyltransferase activity by BRPF2. Nucleic Acids Res. (2017)
  29. Shuyi Ji, Linying Zhu, Yimeng Gao, Xiaoran Zhang, Yupeng Yan, Jin Cen, Rongxia Li, Rong Zeng, Lujian Liao, Chunhui Hou, Yawei Gao, Shaorong Gao, Gang Wei, Lijian Hui. Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening. Cell Res. (2017)
  30. Rekha Rai, Chunyi Hu, Cayla Broton, Yong Chen, Ming Lei, Sandy Chang. NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres. Mol Cell. (2017) 65,1-17.
  31. Zhan Xu, Matthew B. Greenblatt, Guang Yan, Heng Feng, Jun Sun, Sutada Lotinun, Nicholas Brady, Roland Baron, Laurie H. Glimcher, Weiguo Zou. SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts. Nat Commun. (2017) 8,14570.
  32. Jun Chen, Shengbao Suo, Patrick PL Tam, Jingdong J Han, Guangdun Peng, Naihe Jing. Spatial transcriptomic analysis of cryosectioned tissue samples with Geo-seq. Nat Protoc. (2017) 12,566–580.
  33. Lingling Chen, Li Yang. ALUternative regulation for gene expression. Trends Cell Biol. (2017)
  34. Zhanyu Ding, Zhenglin Fu, Cong Xu, Yifan Wang, Yanxing Wang, Junrui Li, Liangliang Kong, Jinhuan Chen, Na Li, Rongguang Zhang, Yao Cong. High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx. Cell Res. (2017)
  35. Feng Wang, Xing Fu, Peng Chen, Ping Wu, Xiaojuan Fan, Na Li, Hong Zhu, Ting-Ting Jia, Hongbin Ji, Zefeng Wang, Catherine C L Wong, Ronggui Hu, Jingyi Hui. SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling. Cell Res. (2017)
  36. Shi Jiao, Chuanchuan Li, Qian Hao, Haofei Miao, Lei Zhang, Lin Li, Zhaocai Zhou. VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer. Nat Commun. (2017) 8,14058.
  37. Xiaoyan Xu, Lei Han, Guixian Zhao, Shengjie Xue, Yunzhen Gao, Jun Xiao, Shicheng Zhang, Peng Chen, Zhiying Wu, Jianping Ding, Ronggui Hu, Bin Wei, Hongyan Wang. LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis. J Exp Med. (2017) 214,209-226.
  38. Jingyao Zhao, Xufeng Chen, Guangrong Song, Jiali Zhang, Haifeng Liu, Xiaolong Liu. Uhrf1 controls the self-renewal versus differentiation of hematopoietic stem cells by epigenetically regulating the cell-division modes. Proc Natl Acad Sci USA. (2017) 114,E142-E151.
  39. Hongli Hu, Wenwei Zhu, Jun Qin, Min Chen, Liyan Gong, Long Li, Xiangyuan Liu, Yongzhen Tao, Huiyong Yin, Hu Zhou, Lisha Zhou, Dan Ye, Qinghai Ye, Daming Gao. Acetylation of PGK1 Promotes Liver Cancer Cell Proliferation and Tumorigenesis. Hepatology. (2017) 65,515-528.
  40. Ji Liang, Ruixiu Cao, Xiongjun Wang, Yajuan Zhang, Pan Wang, Hong Gao, Chen Li, Fan Yang, Rong Zeng, Ping Wei, Dawei Li, Wenfeng Li, Weiwei Yang. Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2. Cell Res.(2017)27:329-351.

2016

  1. Wenshuai Wang, Xiaoyu Sun, Yanbing Li, Jinpeng Su, Zhiyang Ling, Tianlong Zhang, Fang Wang, Hong Zhang, Hualan Chen, Jianping Ding, Bing Sun. Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses. Nat Commun. (2016) 7,13577.
  2. Wenjuan Pu, Hui Zhang, Xiuzhen Huang, Xueying Tian, Lingjuan He, Yue Wang, Libo Zhang, Qiaozhen Liu, Yan Li, Yi Li, Huan Zhao, Kuo Liu, Jie Lu, Yingqun Zhou, Pengyu Huang, Yu Nie, Yan Yan, Lijian Hui, Kathy O. Lui, Bin Zhou. Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration. Nat Commun. (2016) 7,13369.
  3. Liling Xu, Mengdie Xia, Jun Guo, Xiaolin Sun, Hua Li, Chenguang Xu, Xiaomei Gu, Haowen Zhang, Junyang Yi, Yan Fang, Hengyi Xie, Jing Wang, Zhixun Shen, Boxin Xue, Yujie Sun, Tobias Meckel, Yinghua Chen, Zhibin Hu, Zhanguo Li, Chenqi Xu, Haipeng Gong, Wanli Liu. Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupusassociated polymorphism FcγRIIB-T232. J Exp Med. (2016) 213,2707-727.
  4. Longxing Cao, Haishuang Chang, Xiangyi Shi, Chao Peng, Yongning He. Keratin mediates the recognition of apoptotic and necrotic cells through dendritic cell receptor DEC205/CD205. Proc Natl Acad Sci USA. (2016) 113,13438-443.
  5. Huang Wu, Qingfei Yin, Zheng Luo, Runwen Yao, Chuanchuan Zheng, Jun Zhang, Jianfeng Xiang, Li Yang, Lingling Chen. Unusual Processing Generates SPA LncRNAs that Sequester Multiple RNA Binding Proteins. Mol Cell. (2016) 64,534-548. Cover story, Commentary
  6. Yunxiang Zang, Mingliang Jin, Huping Wang, Zhicheng Cui, Liangliang Kong, Caixuan Liu, Yao Cong. Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM. Nat Struct Mol Biol. (2016) 23,1083-1091.
  7. Haiqiang Dai, Bangan Wang, Lu Yang, Jiajia Chen, Guochun Zhu, Meiling Sun, Hao Ge, Rui Wang, Deborah L.Chapman, Fuchou Tang, Xin Sun, Guoliang Xu. TET-mediated DNA demethylation controls gastrulation by regulating Lefty–Nodal signalling. Nature. (2016) 538,528-532.
  8. Lingling Chen, Claw KG, Ramachandran S. A two-fold challenge: the experience of women of color in genomics. Genome Biol. (2016) 17,210.
  9. Wei Wu, Xiaoshan Shi, Chenqi Xu. Regulation of T cell signalling by membrane lipids. Nat Rev Immunol. (2016) 16,690-701.
  10. Fei Li, Zhaoyuan Fang, Jian Zhang, Chen Li, Hongyan Liu, Jufeng Xia, Hongwen Zhu, Chenchen Guo, Zhen Qin, Fuming Li, Xiangkun Han, Yuetong Wang, Yan Feng, Ye Wang, Wenjing Zhang, Zuoyun Wang, Yujuan Jin, Yihua Sun, Wenyi Wei, Rong Zeng, Haiquan Chen, Hongbin Ji. Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma. Cell Res. (2016) 26,1149-164.
  11. Dan Li, Weiping Li, Lijian Hui. Hybrid hepatocyte: A newly identified player for regeneration in hepatic injuries. Hepatology. (2016) 64,2244-246.
  12. Li Mao, Chenglin Liu, Zhen Wang, Xiaofeng Niu, Liang Xue, Zhilei Zhou, Zhenying Cai, Meng Yu, Yixue Li, Dianqing Wu, Lin Li. A genome-wide loss-of-function screening method for minimizing false-negatives caused by functional redundancy. Cell Res. (2016) 26,1067-1070.
  13. Hao Du, Ya Zhao, Jinqiu He, Yao Zhang, Hairui Xi, Mofang Liu, Jinbiao Ma, Ligang Wu. YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex. Nat Commun. (2016) 7,12626.
  14. Wanli Liu, Haopeng Wang, Chenqi Xu. Antigen Receptor Nanoclusters: Small Units with Big Functions. Trends Immunol. (2016) 37,680-689. [REVIEW]
  15. Lingling Chen. Linking Long Noncoding RNA Localization and Function. Trends Biochem Sci. (2016) 41,761-772. [Review] TrendsTalk
  16. Ji Liang, Ruixiu Cao, Yajuan Zhang, Yan Xia, Yanhua Zheng, Xinjian Li, Liwei Wang, Weiwei Yang, Zhimin Lu. PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis. Nat Commun. (2016) 7,12431.
  17. Xiaoou Zhang, Rui Dong, Yang Zhang, Jialin Zhang, Zheng Luo, Jun Zhang, Lingling Chen, Li Yang. Diverse alternative back-splicing and alternative splicing landscape of circular RNAs. Genome Res. (2016) 26,1277-287.
  18. Qing Cissy Yu, Wenqian Song, Daisong Wang, Yi Arial Zeng. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Res. (2016) 26,1079-1098.
  19. Cuiqing Zhong, Meiling Zhang, Qi Yin, Han Zhao, Yang Wang, Sexin Huang, Wenrong Tao, Keliang Wu, Zijiang Chen, Jinsong Li. Generation of human haploid embryonic stem cells from parthenogenetic embryos obtained by microsurgical removal of male pronucleus. Cell Res. (2016) 26,743-746.
  20. Dan Li, Jing Fu, Min Du, Haibin Zhang, Lu Li, Jin Cen, Weiyun Li, Xiaotao Chen, Yunfei Lin, Edward M. Conway, Eli Pikarsky, Hongyan Wang, Guoyu Pan, Yuan Ji, Hongyang Wang, Lijian Hui. Hepatocellular carcinoma repression by TNFα-mediated synergistic lethal effect of mitosis defect-induced senescence and cell death sensitization. Hepatology. (2016) 64,1105-120.
  21. Kirill Oxenoid, Ying Dong, Chan Cao, Tanxing Cui, Yasemin Sancak, Andrew L. Markhard, Zenon Grabarek, Liangliang Kong, Zhijun Liu, Bo Ouyang, Yao Cong, Vamsi K. Mootha, James J. Chou. Architecture of the Mitochondrial Calcium Uniporter. Nature. (2016) 533,269-273.
  22. Rui Shao, Jia Liu, Guang Yan, Jinfang Zhang, Yujiao Han, Jianfeng Guo, Zhan Xu, Zhu Yuan, Jiankang Liu, Marcos Malumbres, Lixin Wan, Wenyi Wei, Weiguo Zou. Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid. Cell Res. (2016) 26,699-712.
  23. Juan Zhao, Yiwei Zhou, Xiujun Zhang, Luonan Chen. Part mutual information for quantifying direct associations in networks. Proc Natl Acad Sci U S A. (2016) 113,5130-135.
  24. Ronggui Hu, Mark Hochstrasser. Recent progress in ubiquitin and ubiquitin-like protein (Ubl) signaling. Cell Res. (2016) 26,389-390. [EDITORIAL]
  25. Zhen Liu, Xiao Yao, Guang Yan, Yichi Xu, Jun Yan, Weiguo Zou, Gang Wang. Mediator MED23 cooperates with RUNX3 to drive osteoblast differentiation and bone development. Nat Commun. (2016) 7,11149.
  26. Xiangdong Lv, Zhijun Han, Hao Chen, Bo Yang, Xiaofeng Yang, Yuanxin Xia, Chenyu Pan, Lin Fu, Shuo Zhang, Hui Han, Min Wu, Zhaocai Zhou, Lei Zhang, Lin Li, Gang Wei, Yun Zhao. A positive role for polycomb in transcriptional regulation via H4K20me1. Cell Res. (2016) 26,529-542.
  27. Guangdun Peng, Shengbao Suo, Jun Chen, Weiyang Chen, Chang Liu, Fang Yu, Ran Wang, Shirui Chen, Na Sun, Guizhong Cui, Lu Song, Patrick P.L. Tam, Jing-Dong J. Han, Naihe Jing. Spatial Transcriptome for the Molecular Annotation of Lineage Fates and Cell Identity in Mid-gastrula Mouse Embryo. Dev Cell. (2016) 36,681-697.
  28. Wei Yang, Yibing Bai, Ying Xiong, Jin Zhang, Shuokai Chen, Xiaojun Zheng, Xiangbo Meng, Lunyi Li, Jing Wang, Chenguang Xu, Chengsong Yan, Lijuan Wang, Catharine C. Y. Chang, Tayuan Chang, Ti Zhang, Penghui Zhou, Baoliang Song, Wanli Liu, Shaocong Sun, Xiaolong Liu, Boliang Li, Chenqi Xu. Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism. Nature. (2016) 531,651-655. Commentary 1 Commentary 2
  29. Lingling Chen. The biogenesis and emerging roles of circular RNAs. Nat Rev Mol Cell Biol. (2016) 17,205-211.
  30. Yanjing Li, Jianming Han, Yuebin Zhang, Fang Cao, Zhijun Liu, Shuai Li, Jian Wu, Chunyi Hu, Yan Wang, Jin Shuai, Juan Chen, Liaoran Cao, Dangsheng Li, Pan Shi, Changlin Tian, Jian Zhang, Yali Dou, Guohui Li, Yong Chen, Ming Lei. Structural basis for activity regulation of MLL family methyltransferases. Nature. (2016) 530,447-452.
  31. Xiaolei Shi, Yimeng Gao, Yupeng Yan, Hucheng Ma, Lulu Sun, Pengyu Huang, Xuan Ni, Ludi Zhang, Xin Zhao, Haozhen Ren, Dan Hu, Yan Zhou, Feng Tian, Yuan Ji, Xin Cheng, Guoyu Pan, Yitao Ding, Lijian Hui. Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes. Cell Res. (2016) 26,206-216.
  32. Cuiqing Zhong, Zhenfei Xie, Qi Yin, Rui Dong, Suming Yang, Yuxuan Wu, Li Yang, Jinsong Li. Parthenogenetic haploid embryonic stem cells efficiently support mouse generation by oocyte injection. Cell Res. (2016) 26,131-134.

2015年

  1. Zimu Deng, Haifeng Liu, Xiaolong Liu. RAG1-mediated ubiquitylation of histone H3 is required for chromosomal V(D)J recombination. Cell Res. (2016) 25,181-192.
  2. Lin Cheng, Longfei Gao, Wuqiang Guan, Jianxin Mao, Wenxiang Hu, Binlong Qiu, Jian Zhao, Yongchun Yu, Gang Pei. Direct conversion of astrocytes into neuronal cells by drug cocktail. Cell Res. (2016) 25,1269-272.
  3. Jianhuang Xue, Guoliang Xu. RNA Pol II as a sensor of 5caC. Cell Res. (2016) 25,1089-1090.
  4. Bowen Yu, Madeline Cassani, Min Wang, Mofang Liu, Jinbiao Ma, Guohong Li, Zhao Zhang, Ying Huang. Structural insights into Rhino-mediated germline piRNA cluster formation. Cell Res. (2016) 25,525-528.
  5. Katie Powis, Tianlong Zhang, Nicolas Panchaud, Rong Wang, Claudio De Virgilio, Jianping Ding. Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling. Cell Res. (2016) 25,1043-1059.
  6. Peng Zhang, Junyan Kang, Lantao Gou, Jiajia Wang, Yuanchao Xue, Geir Skogerboe, Peng Dai, Dawei Huang, Runsheng Chen, Xiangdong Fu, Mofang Liu, Shunmin He. MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes. Cell Res. (2016) 25,193-207.
  7. Yuning Wei, Haiyang Hu, Gangcai Xie, Ning Fu, Zhibin Ning, Rong Zeng, Philipp Khaitovich. Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging. Genome Biol. (2016) 16,41.
  8. Qian Hao,Shi Jiao, Zhubing Shi, Chuanchuan Li, Xia Meng, Zhen Zhang, Yanyan Wang, Xiaomin Song, Wenjia Wang, Rongguang Zhang, Yun Zhao, Catherine CL Wong, Zhaocai Zhou. A non-canonical role of the p97 complex in RIG-I antiviral signaling. EMBO J. (2016) 34,2903-920.
  9. Yuanyuan Ma, Lijie Wu, Neil Shaw, Yan Gao, Jin Wang, Yuna Sun, Zhiyong Lou, Liming Yan, Rongguang Zhang, Zihe Rao. Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex. Proc Natl Acad Sci U S A. (2016) 112,9436-441.
  10. Bingbing Wan, Ting Tang, Heather Upton, Jin Shuai, Yuanzhe Zhou, Song Li, Juan Chen, Joseph S Brunzelle, Zhixiong Zeng, Kathleen Collins, Jian Wu, Ming Lei. The Tetrahymena telomerase p75–p45–p19 subcomplex is a unique CST complex. Nat Struct Mol Biol. (2015) 22,1023-1026.
  11. Weiyun Li, Jun Xiao, Xin Zhou, Ming Xu, Chaobo Hu, Xiaoyan Xu, Yao Lu, Chang Liu, Shengjie Xue, Lei Nie, Haibin Zhang, Zhiqi Li, Yanbo Zhang, Fu Ji, Lijian Hui, Wufan Tao, Bin Wei, Hongyan Wang. STK4 regulates TLR pathways and protects against chronic inflammation–related hepatocellular carcinoma. J Clin Invest. (2015) 125,4239-254.
  12. Qian Hao, Shi Jiao, Zhubing Shi, Chuanchuan Li, Xia Meng, Zhen Zhang, Yanyan Wang, Xiaomin Song, Wenjia Wang, Rongguang Zhang, Yun Zhao, Catherine CL Wong, Zhaocai Zhou. A non‐canonical role of the p97 complex in RIG‐I antiviral signaling. EMBO J. (2015) 34,2903-920.
  13. Renfu Shang, Fengjuan Zhang, Beiying Xu, Hairui Xi, Xue Zhang, Weihua Wang, Ligang Wu. Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects. Nat Commun. (2015) 6:8430.
  14. Xiangjun Chen, Weiling Pan, Yinqiang Sui, Hua Li, Xiaoshan Shi, Xingdong Guo, Hai Qi, Chenqi Xu, Wanli Liu. Acidic phospholipids govern the enhanced activation of IgG-B cell receptor. Nat Commun. (2015) 6:8552.
  15. Hao Jiang, Xiaonan He, Di Feng, Xueliang Zhu, Yixian Zheng. RanGTP aids anaphase entry through Ubr5-mediated protein turnover. J Cell Biol. (2015) 211,7-18.
  16. Hao Jiang, Shusheng Wang, Yuejia Huang, Xiaonan He, Honggang Cui, Xueliang Zhu, Yixian Zheng. Phase Transition of Spindle-Associated Protein Regulate Spindle Apparatus Assembly. Cell. (2015) 163,108-122.
  17. Yunneng Tang, Weiqiao Ding, Xiaojie Guo, Xinwang Yuan, Dongmei Wang, Jianguo Song. Epigenetic regulation of Smad2 and Smad3 by profilin-2 promotes lung cancer growth and metastasis. Nat Commun. (2015) 6:8230.
  18. Lingfei Zhang, Jiatao Lou, Minghua Lu, Chunfang Gao, Shuang Zhao, Biao Li, Sheng Liang, Yong Li, Dangsheng Li, Mofang Liu. Suppression of miR‐199a maturation by HuR is crucial for hypoxia‐induced glycolytic switch in hepatocellular carcinoma. EMBO J. (2015) 34,2671-685.
  19. Xiao Yao, Zhanyun Tang, Xing Fu, Jingwen Yin, Yan Liang, Chonghui Li, Huayun Li, Qing Tian, Robert G Roeder, Gang Wang. The Mediator subunit MED23 couples H2B mono‐ubiquitination to transcriptional control and cell fate determination. EMBO J. (2015) 34,2885-902.
  20. Wenxiang Hu, Binlong Qiu, Wuqiang Guan, Qinying Wang, Min Wang, Wei Li, Longfei Gao, Lu Shen, Yin Huang, Gangcai Xie, Hanzhi Zhao, Ying Jin, Beisha Tang, Yongchun Yu, Jian Zhao, Gang Pei. Direct Conversion of Normal and Alzheimer’s Disease Human Fibroblasts into Neuronal Cells by Small Molecules. Cell Stem Cell. (2015) 17,204-212. Commentary
  21. Yuheng Shi, Bofeng Yuan, Nan Qi, Wenting Zhu, Jingru Su, Xiaoyan Li, Peipei Qi, Dan Zhang, Fajian Hou. An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response. Nat Commun. (2015) 6,7811.
  22. Cuiqing Zhong, Qi Yin, Zhenfei Xie, Meizhu Bai, Rui Dong, Wei Tang, Yuhang Xing, Hongling Zhang, Suming Yang, Lingling Chen, Marisa S. Bartolomei, Anne Ferguson-Smith, Dangsheng Li, Li Yang, Yuxuan Wu, Jinsong Li. CRISPR-Cas9-Mediated Genetic Screening in Mice with Haploid Embryonic Stem Cells Carrying a Guide RNA Library. Cell Stem Cell. (2015) 17,221-232.
  23. Wei Deng, Jian Wu, Feng Wang, Junko Kanoh, Pierre-Marie Dehe, Haruna Inoue, Juan Chen, Ming Lei. Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2. Cell Res. (2015) 25,881-884.
  24. Lingling Chen, Li Yang. Gear Up in Circles. Mol Cell. (2015) 58,715-717. [Preview]
  25. Longxing Cao, Xiangyi Shi, Haishuang Chang, Qinfen Zhang, Yongning He. pH-dependent recognition of apoptotic and necrotic cells by the human dendritic cell receptor DEC205. Proc Natl Acad Sci USA. (2015) 112,7237-242.
  26. Xin Fu, Jun Xiao, Yuning Wei, Sheng Li, Yan Liu, Jie Yin, Kun Sun, Hao Sun, Huating Wang, Zongkang Zhang, Baoting Zhang, Chun Sheng, Hongyan Wang, Ping Hu. Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion. Cell Res. (2015) 25,655-673.
  27. Fuming Li, Xiangkun Han, Fei Li, Rui Wang, Hui Wang, Yijun Gao, Xujun Wang, Zhaoyuan Fang, Wenjing Zhang, Shun Yao, Xinyuan Tong, Yuetong Wang, Yan Feng, Yihua Sun, Yuan Li, Kwok-Kin Wong, Qiwei Zhai, Haiquan Chen, Hongbin Ji. LKB1 Inactivation Elicits a Redox Imbalance to Modulate Non-small Cell Lung Cancer Plasticity and Therapeutic Response. Cancer Cell. (2015) 27,698-711.
  28. Yihan Wan, Xiaobin Zheng, Haiyang Chen, Yuxuan Guo, Hao Jiang, Xiaonan He, Xueliang Zhu, Yixian Zheng. Splicing function of mitotic regulators links R-loop–mediated DNA damage to tumor cell killing. J Cell Biol. (2015) 209, 235-246. Commentary
  29. Pingyu Liu, Xiaoyang Dou, Chang Liu, Lingbo Wang, Can Xing, Guangdun Peng, Jun Chen, Fang Yu, Yunbo Qiao, Lu Song, Yuxuan Wu, Chunmei Yue, Jinsong Li, Jing-Dong J. Han, Ke Tang, Naihe Jing. Histone deacetylation promotes mouse neural induction by restricting Nodal-dependent mesendoderm fate. Nat Commun. (2015) 6,6830.
  30. Beibei Chu, Yacheng Liao, Wei Qi, Chang Xie, Ximing Du, Jiang Wang, Hongyuan Yang, Honghua Miao, Boliang Li, Baoliang Song. Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts. Cell. (2015) 161,291-306.
  31. Chao Wang, Wenxiang Zhang, Mengxin Yin, Lianxin Hu, Peixue Li, Jiajun Xu, Hongling Huang, Shimin Wang, Yi Lu, Wenqing Wu, Margaret S. Ho, Lin Li, Yun Zhao, Lei Zhang. Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis. Nat Commun. (2015) 6,6607.
  32. Shibin Hu, Jianfeng Xiang, Xiang Li, Yefen Xu, Wei Xue, Min Huang, Catharine C. Wong, Cari A. Sagum, Mark T. Bedford, Li Yang, Donghang Cheng, Lingling Chen. Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus. Genes Dev. (2015) 29,630-645. Commentary
  33. Tian Chen, Jianfeng Xiang, Shanshan Zhu, Siye Chen, Qingfei Yin, Xiaoou Zhang, Jun Zhang, Hua Feng, Rui Dong, Xuejun Li, Li Yang, Lingling Chen. ADAR1 is required for differentiation and neural induction by regulating microRNA processing in a catalytically independent manner. Cell Res. (2015) 25,459-476.
  34. Wenjing Mu, Chaobo Hu, Haibin Zhang, Zengqiang Qu, Jin Cen, Zhixin Qiu, Chao Li, Haozhen Ren, Yixue Li, Xianghuo He, Xiaolei Shi, Lijian Hui. miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression. Cell Res. (2015) 25,477-495.
  35. Shi Jiao, Zhen Zhang, Chuanchuan Li, Min Huang, Zhubing Shi, Yanyan Wang, Xiaomin Song, Heng Liu, Chunyang Li, Min Chen, Wenjia Wang, Yun Zhao, Zhengfan Jiang, Hongyan Wang, Catherine C L Wong, Chen Wang, Zhaocai Zhou. The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6. Nat Immunol. (2015) 16,246-257.
  36. Yuxuan Wu, Hai Zhou, Xiaoying Fan, Ying Zhang, Man Zhang, Yinghua Wang, Zhenfei Xie, Meizhu Bai, Qi Yin, Dan Liang, Wei Tang, Jiaoyang Liao, Chikai Zhou, Wujuan Liu, Ping Zhu, Hongshan Guo, Hong Pan, Chunlian Wu, Huijuan Shi, Ligang Wu, Fuchou Tang, Jinsong Li. Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells. Cell Res. (2015) 25,67-79. Commentary
  37. Daisong Wang, Cheguo Cai, Xiaobing Dong, Qing Cissy Yu, Xiao-Ou Zhang, Li Yang, Yi Arial Zeng. Identification of multipotent mammary stem cells by protein C receptor expression. Nature. (2015) 517,81-84.

2014年

  1. Qiang Wang, Xing Liu, Ye Cui, Yijun Tang, Wei Chen, Senlin Li, Huansha Yu, Youdong Pan, Chen Wang. The E3 Ubiquitin Ligase AMFR and INSIG1 Bridge the Activation of TBK1 Kinase by Modifying the Adaptor STING. Immunity. (2014) 41,919-933. Commentary
  2. Li Yang, Lingling Chen. Microexons Go Big. Cell. (2014) 159,1488-1489. [Preview]
  3. Yajing Chu, Leonardo Gómez Rosso, Ping Huang, Zhichao Wang, Yichi Xu, Xiao Yao, Menghan Bao, Jun Yan, Haiyun Song, Gang Wang. Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity. Cell Res. (2014) 24,1250-265.
  4. Yang Sun, Xiaoyan Zhu, Xufeng Chen, Haifeng Liu, Yu Xu, Yajing Chu, Gang Wang, Xiaolong Liu. The mediator subunit Med23 contributes to controlling T-cell activation and prevents autoimmunity. Nat Commun. (2014) 5:5225.
  5. Cheguo Cai, Qing Cissy Yu, Weimin Jiang, Wei Liu, Wenqian Song, Hua Yu, Lei Zhang, Ying Yang, Yi Arial Zeng. R-spondin1 is a novel hormone mediator for mammary stem cell self-renewal. Genes Dev. (2014) 28,2205-218.
  6. Xiaoou Zhang, Haibin Wang, Yang Zhang, Xuhua Lu, Lingling Chen, Li Yang. Complementary Sequence-Mediated Exon Circularization. Cell. (2014) 159,134-147. Commentary
  7. Tao Yu, Yonghui Tao, Meiqiang Yang, Peng Chen, Xiaobo Gao, Yanbo Zhang, Tao Zhang, Zi Chen, Jian Hou, Yan Zhang, Kangcheng Ruan, Hongyan Wang, Ronggui Hu. Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis. Cell Res. (2014) 24,1214-230.
  8. Fan Guo, Xianlong Li, Dan Liang, Tong Li, Ping Zhu, Hongshan Guo, Xinglong Wu, Lu Wen, Tianpeng Gu, Boqiang Hu, Colum P. Walsh, Jinsong Li, Fuchou Tang, Guoliang Xu. Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote. Cell Stem Cell. (2014) 15,447-458. Commentary
  9. Yijun Gao, Wenjing Zhang, Xiangkun Han, Fuming Li, Xujun Wang, Rui Wang, Zhaoyuan Fang, Xinyuan Tong, Shun Yao, Fei Li, Yan Feng, Yihua Sun, Yingyong Hou, Zhongzhou Yang, Kunliang Guan, Haiquan Chen, Lei Zhang, Hongbin Ji. YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression. Nat Commun. (2014) 5:4629.
  10. Shicheng Zhang, Tianlong Zhang, Minghui Yan, Jianping Ding, Jiangye Chen. Crystal structure of the WOPR-DNA complex and implications for Wor1 function in white-opaque switching of Candida albicans. Cell Res. (2014) 24,1108-120.
  11. Zhengzhao Liu, Peng Chen, Hong Gao, Yu Gu, Jiao Yang, Hong Peng, Xingxing Xu, Haifeng Wang, Meiqiang Yang, Xiaoying Liu, Libin Fan, Shiyao Chen, Jian Zhou, Yihong Sun, Kangchen Ruan, Shuqun Cheng, Masaaki Komatsu, Eileen White, Lin Li, Hongbin Ji, Daniel Finley, Ronggui Hu. Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression. Cancer Cell. (2014) 26,106-120.
  12. Ye Wang, Jing Gao, Xingdong Guo, Ti Tong, Xiaoshan Shi, Lunyi Li, Miao Qi, Yajie Wang, Mingjun Cai, Junguang Jiang, Chenqi Xu, Hongbin Ji, Hongda Wang. Regulation of EGFR nanocluster formation by ionic protein-lipid interaction. Cell Res. (2014) 24,959-976.
  13. Hao Sun, Jie Liu, YaJuan Zheng, YouDong Pan, Kun Zhang, Jianfeng Chen. Distinct Chemokine Signaling Regulates Integrin Ligand Specificity to Dictate Tissue-Specific Lymphocyte Homing. Dev Cell. (2014) 30,61-70.
  14. Xufeng Chen, Jiali Zhang, Jingyao Zhao, Haifeng Liu, Xiang Sun, Mujun Zhao, Xiaolong Liu. Lis1 is required for the expansion of hematopoietic stem cells in the fetal liver. Cell Res. (2014) 24,1013-1016.
  15. Haisen Li, Rui Yue, Bin Wei, Ge Gao, Jiulin Du, Gang Pei. Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. EMBO J. (2014) 33,1383-396.
  16. Jing Huang, Andrew F Brown, Jian Wu, Jing Xue, Christopher J Bley, Dustin P Rand, Lijie Wu, Rongguang Zhang, Julian J-L Chen, Ming Lei. Structural basis for protein-RNA recognition in telomerase. Nat Struct Mol Biol. (2014) 21,507-512.
  17. Lantao Gou, Peng Dai, Jianhua Yang, Yuanchao Xue, Yunping Hu, Yu Zhou, Junyan Kang, Xin Wang, Hairi Li, Minmin Hua, Shuang Zhao, Sida Hu, Ligang Wu, Huijuan Shi, Yong Li, Xiangdong Fu, Lianghu Qu, Enduo Wang, Mofang Liu. Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis. Cell Res. (2014) 24,680-700. Commentary
  18. Jianfeng Xiang, Qingfei Yin, Tian Chen, Yang Zhang, Xiaoou Zhang, Zheng Wu, Shaofeng Zhang, Haibin Wang, Junhui Ge, Xuhua Lu, Li Yang, Lingling Chen. Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus. Cell Res. (2014) 24,513-531. Commentary
  19. Yanbo Zhang, Yao Lu, Li Ma, Xudong Cao, Jun Xiao, Jiexia Chen, Shaozhuo Jiao, Yunzhen Gao, Chang Liu, Zhaojun Duan, Dangsheng Li, Yulong He, Bin Wei, Hongyan Wang. Activation of Vascular Endothelial Growth Factor Receptor-3 in Macrophages Restrains TLR4-NF-κB Signaling and Protects against Endotoxin Shock. Immunity. (2014) 40,501-514.
  20. Lin Cheng, Wenxiang Hu, Binlong Qiu, Jian Zhao, Yongchun Yu, Wuqiang Guan, Min Wang, Wuzhou Yang, Gang Pei. Generation of neural progenitor cells by chemical cocktails and hypoxia. Cell Res. (2014) 24,665-679. Commentary
  21. Pengyu Huang, Ludi Zhang, Yimeng Gao, Zhiying He, Dan Yao, Zhitao Wu, Jin Cen, Xiaotao Chen, Changcheng Liu, Yiping Hu, Dongmei Lai, Zhenlei Hu, Li Chen, Ying Zhang, Xin Cheng, Xiaojun Ma, Guoyu Pan, Xin Wang, Lijian Hui. Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes. Cell Stem Cell. (2014) 14,370-384. Commentary
  22. Lunyi Li, Xiaoshan Shi, Xingdong Guo, Hua Li, Chenqi Xu. Ionic protein–lipid interaction at the plasma membrane: what can the charge do? Trends Biochem Sci. (2014) 39,130-140. [Review]
  23. Xiangkun Han, Fuming Li, Zhaoyuan Fang, Yijun Gao, Fei Li, Rong Fang, Shun Yao, Yihua Sun, Li Li, Wenjing Zhang, Huimin Ma, Qian Xiao, Gaoxiang Ge, Jing Fang, Hongda Wang, Lei Zhang, Kwok-kin Wong, Haiquan Chen, Yingyong Hou, Hongbin Ji. Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma. Nat Commun. (2014) 5:3261.
  24. Xiao Hu, Lei Zhang, Shiqing Mao, Zheng Li, Jiekai Chen, Runrui Zhang, Haiping Wu, Juan Gao, Fan Guo, Wei Liu, Guifang Xu, Haiqiang Dai, Yujiang Geno Shi, Xianlong Li, Boqiang Hu, Fuchou Tang, Duanqing Pei, Guoliang Xu. Tet and TDG Mediate DNA Demethylation Essential for Mesenchymal-to-Epithelial Transition in Somatic Cell Reprogramming. Cell Stem Cell. (2014) 14,512-522. Commentary
  25. Shi Jiao, Huizhen Wang, Zhubing Shi, Aimei Dong, Wenjing Zhang, Xiaomin Song, Feng He, Yicui Wang, Zhenzhen Zhang, Wenjia Wang, Xin Wang, Tong Guo, Peixue Li, Yun Zhao, Hongbin Ji, Lei Zhang, Zhaocai Zhou. A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer. Cancer Cell. (2014) 25,166-180.
  26. Wenjing Zhang, Yijun Gao, Peixue Li, Zhubing Shi, Tong Guo, Fei Li, Xiangkun Han, Yan Feng, Chao Zheng, Zuoyun Wang, Fuming Li, Haiquan Chen, Zhaocai Zhou, Lei Zhang, Hongbin Ji. VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex. Cell Res. (2014) 24,331-343.
  27. Hao Jiang, Xiaonan He, Shusheng Wang, Junling Jia, Yihan Wan, Yueju Wang, Rong Zeng, John Yates III, Xueliang Zhu, Yixian Zheng. A Microtubule-Associated Zinc Finger Protein, BuGZ, Regulates Mitotic Chromosome Alignment by Ensuring Bub3 Stability and Kinetochore Targeting. Dev Cell. (2014) 28,268-281. Commentary
  28. Yanni Zhang, Ke Xu, Anqi Deng, Xing Fu, Anlong Xu, Xiaolong Liu. An amphioxus RAG1-like DNA fragment encodes a functional central domain of vertebrate core RAG1. Proc Natl Acad Sci USA. (2014) 111,397-402.
  29. Peishan Li, Zhenyan Fu, Yingyu Zhang, Jinhui Zhang, Chenqi Xu, Yitong Ma, Boliang Li, Baoliang Song. The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1. Nat Med. (2014) 20,80-86.
  30. Song Hu, Wei Zhu, Lingfei Zhang, Ming Pei, Mofang Liu. MicroRNA-155 broadly orchestrates inflammation-induced changes of microRNA expression in breast cancer. Cell Res. (2014) 24,254-257.

2013年

  1. Yuxuan Wu, Dan Liang, Yinghua Wang, Meizhu Bai, Wei Tang, Shiming Bao, Zhiqiang Yan, Dangsheng Li, Jinsong Li. Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9. Cell Stem Cell. (2013) 13,659-662.
  2. Zhao Zhang, Jing Feng, Chenyu Pan, Xiangdong Lv, Wenqing Wu, Zhaocai Zhou, Feng Liu, Lei Zhang, Yun Zhao. Atrophin-Rpd3 complex represses Hedgehog signaling by acting as a corepressor of CiR. J Cell Biol. (2013) 203:575-583.
  3. Shoujun Huang, Zhao Zhang, Chunxia Zhang, Xiangdong Lv, Xiudeng Zheng, Zhenping Chen, Liwei Sun, Hailong Wang, Yuanxiang Zhu, Jing Zhang, Shuyan Yang, Yi Lu, Qinmiao Sun, Yi Tao, Feng Liu, Yun Zhao, Dahua Chen. Activation of Smurf E3 ligase promoted by Smoothened regulates Hedgehog signaling through targeting Patched turnover. PLoS Biology. (2013) 11,e1001721.
  4. Yan Zhang, Lin Fu, Xiaolong Qi, Zhenyi Zhang, Yuanxin Xia, Jianhang Jia, Jin Jiang, Yun Zhao, Geng Wu. Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun. (2013) 4:2608.
  5. Huijie Zhao, Lei Zhu, Yunlu Zhu, Jingli Cao, Shanshan Li, Qiongping Huang, Tao Xu, Xiao Huang, Xiumin Yan, Xueliang Zhu. The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis. Nat Cell Biol. (2013) 15,1434-444.
  6. Jiekai Chen, Lin Guo, Lei Zhang, Haoyu Wu, Jiaqi Yang, He Liu, Xiaoshan Wang, Xiao Hu, Tianpeng Gu, Zhiwei Zhou, Jing Liu, Jiadong Liu, Hongling Wu, Shiqing Mao, Kunlun Mo, Yingying Li, Keyu Lai, Jing Qi, Hongjie Yao, Guangjin Pan, Guoliang Xu, Duanqing Pei. Vitamin C modulates TET1 function during somatic cell reprogramming. Nat Genet. (2013) 45,1504-509.
  7. Yang Zhang, Xiaoou Zhang, Tian Chen, Jianfeng Xiang, Qingfei Yin, Yuhang Xing, Shanshan Zhu, Li Yang, Lingling Chen. Circular Intronic Long Noncoding RNAs. Mol Cell. (2013) 51,792-806. Commentary
  8. Tong Guo, Yi Lu, Peixue Li, Mengxin Yin, Dekang Lv, Wenjing Zhang, Huizhen Wang, Zhaocai Zhou, Hongbin Ji, Yun Zhao, Lei Zhang. A novel partner of Scalloped regulates Hippo signaling via antagonizing Scalloped-Yorkie activity. Cell Res. (2013) 23,1201-214.
  9. Hongling Huang, Shimin Wang, Mengxin Yin, Liang Dong, Chao Wang, Wei Wu, Yi Lu, Miao Feng, Chuanyang Dai, Xiaocan Guo, Li Li, Bin Zhao, Zhaocai Zhou, Hongbin Ji, Jin Jiang, Yun Zhao, Xinyuan Liu, Lei Zhang. Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association. PLoS Biol. (2013) 11,e1001620.
  10. Shutong Xu, Wenjing Li, Junjun Zhu, Rong Wang, Zheng Li, Guoliang Xu, Jianping Ding. Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res. (2013) 23,1296-309.
  11. Weiguo Zou, Matthew B. Greenblatt, Nicholas Brady, Sutada Lotinun, Bo Zhai, Heather de Rivera, Anju Singh, Jun Sun, Steven P. Gygi, Roland Baron, Laurie H. Glimcher, Dallas C. Jones. The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2. J Exp Med. (2013) 210,1793-806.
  12. Sheng Wang, Junlin Yin, Duozhi Chen, Fen Nie, Xiaomin Song, Cong Fei, Haofei Miao, Changbin Jing, Wenjing Ma, Lei Wang, Sichun Xie, Chen Li, Rong Zeng, Weijun Pan, Xiaojiang Hao, Lin Li. Small-molecule modulation of Wnt signaling via modulating the Axin-LRP 5/6 interaction. Nat Chem Biol. (2013) 9,579-585.
  13. Hui Yang, Zhen Liu, Yu Ma, Cuiqing Zhong, Qi Yin, Chikai Zhou, Linyu Shi, Yijun Cai, Hanzhi Zhao, Hui Wang, Fan Tang, Yan Wang, Chenchen Zhang, Xinyuan Liu, Dongmei Lai, Ying Jin, Qiang Sun, Jinsong Li. Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes. Cell Res. (2013) 23,1187-200.
  14. Guangjing Hu, Jia Chen, Xiaonan Zhao, Jiajia Xu, Dongqing Guo, Ming Lu, Ming Zhu, Ying Xiong, Qin Li, Catherine CY Chang, Baoliang Song, Tayuan Chang, Boliang Li. Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene. Cell Res. (2013) 23,1007-1024.
  15. Dan Li, Jin Cen, Xiaotao Chen, Edward M.Conway, Yuan Ji, Lijian Hui. Hepatic loss of survivin impairs postnatal liver development and promotes expansion of hepatic progenitor cells. Hepatology. (2013) 58,2109-121.
  16. Runrui Zhang, Qingyan Cui, Kiyohito Murai, Yen Ching Lim, Zachary D.Smith, Shengnan Jin, Peng Ye, Luis Rosa, Yew Kok Lee, Haiping Wu, Wei Liu, Zhimei Xu, Lu Yang, Yuqiang Ding, Fuchou Tang, Alexander Meissner, Chunming Ding, Yanhong Shi, Guoliang Xu. Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition. Cell Stem Cell. (2013) 13,237-245. Commentary
  17. Bo OuYang, Shiqi Xie, Marcelo J.Berardi, Xinhao Zhao, Jyoti Dev, Wenjing Yu, Bing Sun, James J. Chou. Unusual architecture of the p7 channel from hepatitis C virus. Nature. (2013) 498,521-525.
  18. Zhao Zhang, Xiangdong Lv, Wenchi Yin, Xiaoyun Zhang, Jing Feng, Wenqing Wu, Chichung Hui, Lei Zhang, Yun Zhao. Ter94 ATPase Complex Targets K11-Linked Ubiquitinated Ci to Proteasomes for Partial Degradation. Dev Cell. (2013) 25,636-644.
  19. Juan Li, Bin Wei, Ao Guo, Chang Liu, Shichao Huang, Fang Du, Wei Fan, Chunde Bao, Gang Pei. Deficiency of β-arrestin1 ameliorates collagen-induced arthritis with impaired TH17 cell differentiation. Proc Natl Acad Sci USA. (2013) 110,7395-400.
  20. Xiaosong Liu, Xiaohui Zhao, Xianglu Zeng, Koen Bossers, Dick F Swaab, Jian Zhao, Gang Pei. β-Arrestin1 regulates γ-secretase complex assembly and modulates amyloid-β pathology. Cell Res. (2013) 23,351-365.
  21. Zhao Zhang, Xiangdong Lv, Jin Jiang, Lei Zhang, Yun Zhao. Dual roles of Hh signaling in the regulation of somatic stem cell self-renewal and germline stem cell maintenance in Drosophila testis. Cell Res. (2013) 23,573-576.
  22. Kairui Mao, Shuzhen Chen, Mingkuan Chen, Yonglei Ma, Yan Wang, Bo Huang, Zhengyu He, Yan Zeng, Yu Hu, Shuhui Sun, Jing Li, Xiaodong Wu, Xiangrui Wang, Warren Strober, Chang Chen, Guangxun Meng, Bing Sun. Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Cell Res. (2013) 23,201-212.
  23. Jie Yan, Jialing Xiang, Yutin Lin, Jingui Ma, Jiyan Zhang, Hao Zhang, Jisheng Sun, Nika N.Dania, Jing Liu, Anning Lin. Inactivation of BAD by IKK Inhibits TNFα-Induced Apoptosis Independently of NF-κB Activation. Cell. (2013) 152,304-315.
  24. Shuang Zhao, Lantao Gou, Man Zhang, Lidong Zu, Minmin Hua, Ye Hua, Huijuan Shi, Yong Li, Jinsong Li, Dangsheng Li, Enduo Wang, Mofang Liu. piRNA-triggered MIWI ubiquitination and removal by APC/C in late spermatogenesis. Dev Cell. (2013) 24,13-25.
  25. Xiaoshan Shi, Yunchen Bi, Wei Yang, Xingdong Guo, Yan Jiang, Chanjuan Wan, Lunyi Li, Yibing Bai, Jun Guo, Yujuan Wang, Xiangjun Chen, Bo Wu, Hongbin Sun, Wanli Liu, Junfeng Wang, Chenqi Xu. Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids. Nature. (2013) 493,111-115.
  26. Jing Jiang, Wenjian Lv, Xiaoying Ye, Lingbo Wang, Man Zhang, Hui Yang, Maja Okuka, Chikai Zhou, Xuan Zhang, Lin Liu, Jinsong Li. Zscan4 promotes genomic stability during reprogramming and dramatically improves the quality of iPS cells as demonstrated by tetraploid complementation. Cell Res. (2013) 23,92-106.

2012年

  1. Lihua Min, Yuan Ji, Latifa Bakiri, Zhixin Qiu, Jin Cen, Xiaotao Chen, Lingli Chen, Harald Scheuch, Hai Zheng, Lunxiu Qin, Kurt Zatloukal, Lijian Hui, Erwin F.Wagner. Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of Survivin. Nat Cell Biol. (2012) 14,1203-211.
  2. Xu Yang, Meng Zhao, Min Xia, Yuting Liu, Jun Yan, Hongbin Ji, Gang Wang. Selective Requirement for Mediator MED23 in Ras-active Lung Cancer. Proc Natl Acad Sci USA. (2012) 109,E2813-822.
  3. Jingwen Yin, Yan Liang, Ji Yeon Park, Dongrui Chen, Xiao Yao, Qi Xiao, Zhen Liu, Bo Jiang, Yu Fu, Menghan Bao, Yan Huang, Yuting Liu, Jun Yan, Minsheng Zhu, Zhongzhou Yang, Pingjin Gao, Bin Tian, Dangsheng Li, Gang Wang. Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation. Genes Dev. (2012) 26,2192-205.
  4. Gang Xiao, Anqi Deng, Haifeng Liu, Gaoxiang Ge, Xiaolong Liu. Activator protein 1 suppresses antitumor T-cell function via the induction of programmed death 1. Proc Natl Acad Sci USA. (2012) 109,15419-424.
  5. Qingfei Yin, Li Yang, Yang Zhang, Jianfeng Xiang, Yuewei Wu, Gordon G.Carmichael, Lingling Chen. Long Noncoding RNAs with snoRNA Ends. Mol Cell. (2012) 48,219-230. Commentary 1 Commentary 2
  6. Tongfei Liu, Jingjie Tang, Peishan Li, Yang Shen, Jiagui Li, Honghua Miao, Boliang Li, Baoliang Song. Ablation of gp78 in liver improves hyperlipidemia and insulin resistance by inhibiting SREBP to decrease lipid biosynthesis. Cell Metab. (2012) 16,213-225.
  7. Jingli Cao, Yidong Shen, Lei Zhu, Yanan Xu, Yizhuo Zhou, Zhili Wu, Yiping Li, Xiumin Yan, Xueliang Zhu. miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics. Nat Cell Biol. (2012) 14,697-706.
  8. Hui Yang, Linyu Shi, Bangan Wang,Dan Liang, Cuiqing Zhong, Wei Liu, Yongzhan Nie, Jie Liu, Jing Zhao, Xiang Gao, Dangsheng Li, Guoliang Xu, Jinsong Li. Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells. Cell. (2012) 149,605-617.
  9. Rui Yue, Haisen Li, Huan Liu, Yuanyuan Li, Bin Wei, Ge Gao, Yi Jin, Tingxi Liu, Liping Wei, Jiulin Du, Gang Pei. Thrombin Receptor Regulates Hematopoiesis and Endothelial-to-Hematopoietic Transition. Dev Cell. (2012) 22,1092-100.
  10. Shuai Jiang, Lingfei Zhang, Hongwei Zhang, Song Hu, Minghua Lu, Sheng Liang, Biao Li, Yong Li, Dangsheng Li, Enduo Wang, Mofang Liu. A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells. EMBO J. (2012) 31,1985-998.
  11. Yan Huang, Wencheng Li, Xiao Yao, Qijiang Lin, Jingwen Yin, Yan Liang, Monika Heiner, Bin Tian, Jingyi Hui, Gang Wang. Mediator Complex Regulates Alternative mRNA Processing via the Med23 Subunit. Mol Cell. (2012) 45,459-469.
  12. Jing Liu, Jie Yana, Shan Jiang, Jing Wen, Long Chen, Yingming Zhao, Anning Lin. Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-α-induced JNK activation and inflammation. Proc Natl Acad Sci USA. (2012) 109,191-196.

2011年

  1. Tianpeng Gu, Fan Guo, Hui Yang, Haiping Wu, Guifang Xu, Wei Liu, Zhiguo Xie, Linyu Shi, Xinyi He, Seunggi Jin, Khursheed Iqbal, Yujiang Geno Shi, Zixin Deng, Piroska E.Szabó, Gerd P.Pfeifer, Jinsong Li, Guoliang Xu. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature. (2011) 477,606-610.
  2. Yufei He, Binzhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li, Yan Sun, Xiuxue Li, Qing Dai, Chunxiao Song, Kangling Zhang, Chuan He, Guoliang Xu. Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA. Science. (2011) 333,1303-307.Commentary
  3. Zhihui Xie, Yongfeng Chen, Zhenfei Li, Ge Bai, Yue Zhu, Rui Yan, Fangzhi Tan, Yeguang Chen, Francois Guillemot, Lin Li, Naihe Jing. Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube by inhibition of the Wnt/β-catenin pathway. Proc Natl Acad Sci USA. (2011) 108,12119-124.
  4. Pengyu Huang, Zhiying He, Shuyi Ji, Huawang Sun, Dao Xiang, Changcheng Liu, Yiping Hu, Xin Wang, Lijian Hui. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature. (2011) 475,386-389. Commentary 1 Commentary 2
  5. Yuelei Chen, Jing Lv, Xiaolei Ye, Mingyu Sun, Qin Xu, Chenghai Liu, Lihua Min, Huiping Li, Ping Liu, Xiaoyan Ding. Sorafenib Inhibits Transforming Growth Factor β1-Mediated Epithelial-Mesenchymal Transition and Apoptosis in Mouse Hepatocytes. Hepatology. (2011) 53,1708-718.
  6. Yonghao Cao, Hai Li, Haifeng Liu, Min Zhang, Zichun Hua, Hongbin Ji, Xiaolong Liu. LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection. EMBO J. (2011) 30,2083-2093.
  7. Jiangwei Lin, Linyu Shi, Man Zhang, Hui Yang, Yiren Qin, Jun Zhang, Daoqing Gong, Xuan Zhang, Dangsheng Li, Jinsong Li. Defects in trophoblast cell lineage account for the impaired in vivo development of cloned embryos generated by somatic nuclear transfer. Cell Stem Cell. (2011) 8,371-375.
  8. Minyun Zhou, Xianchi Dong, Carsten Baldauf, Hua Chen, Yanfeng Zhou, Timothy A.Springer, Xinping Luo, Chen Zhong, Frauke Gräter, Jianping Ding. A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13. Blood. (2011) 117,4623-631.
  9. Zhenfei Li, Fen Nie, Sheng Wang, Lin Li. Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation. Proc Natl Acad Sci USA. (2011) 108,3116-123. Commentary
  10. Bo O.Zhou, Shanshan Wang, Yang Zhang, Xiaohong Fu, Wei Dang, Brian A.Lenzmeier, Jinqiu Zhou. Histone H4 Lysine 12 Acetylation Regulates Telomeric Heterochromatin Plasticity in Saccharomyces cerevisiae. PLoS Genet. (2011) 7,e1001272.
  11. Shaoqiu He, Zhenning Zhang, Jisong Guan, Hongrui Liu, Bo Zhao, Haibo Wang, Qian Li, Hong Yang, Jie Luo, Ziyan Li, Qiong Wang, Yingjin Lu, Lan Bao, Xu Zhang. Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor- Mediated Codegradation. Neuron. (2011) 69,120-131.
  12. Zhenhu Li, Yuan Zhang, Zhiduo Liu, Xiaodong Wu, Yuhan Zheng, Zhiyun Tao, Kairui Mao, Jie Wang, Guomei Lin, Lin Tian, Yongyong Ji, Meiling Qin, Shuhui Sun, Xueliang Zhu, Bing Sun. ECM1 controls TH2 cell egress from lymph nodes through re-expression of S1P1. Nat Immunol. (2011) 12,178-185. Commentary
  13. Jingjie Tang, Jiagui Li, Wei Qi, Wenwei Qiu, Peishan Li, Boliang Li, Baoliang Song. Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques. Cell Metab. (2011) 13,44-56. Commentary
  14. Liang Ge, Wei Qi, Lijuan Wang, Honghua Miao, Yuxiu Qu, Boliang Li, Baoliang Song. Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake. Proc Natl Acad Sci USA. (2011) 108,551-556.
  15. Guangming Chen, Liang Da, Hongfei Wang, Ying Xu, Guoyuan Chen, Chengfu Sun, Leiming Wang, Jing Zhao, Fang Zhang, Jian Feng, Yifei Wang, Pierre Tiollais, Tsaiping Li, Mujun Zhao. HIV-Tat-mediated Delivery of an LPTS Functional Fragment Inhibits Telomerase Activity and Tumorigenecity of Hepatoma Cells. Gastroenterology. (2011) 140,332-343.

2010年之前

  1. Youdong Pan, Kun Zhang, Junpeng Qi, Jiao Yue, Timothy A.Springer, Jianfeng Chen. Cation-π interaction regulates ligand-binding affinity and signaling of integrin α4β7. Proc Natl Acad Sci USA. (2010) 107,21388-393.
  2. Yijun Gao, Qian Xiao, HuiMin Ma, Li Li, Jun Liu, Yan Feng, Zhaoyuan Fang, Jing Wu, Xiangkun Han, Junhua Zhang, Yihua Sun, Gongwei Wu, Robert Padera, Haiquan Chen, Kwok-kin Wong, Gaoxiang Ge, Hongbin Ji. LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling. Proc Natl Acad Sci USA. (2010) 107,18892-897.
  3. Nengyin Sheng, Zhihui Xie, Chen Wang, Ge Bai, Kejing Zhang, Qingqing Zhu, Jianguo Song, Francois Guillemot, Yeguang Chen, Anning Lin, Naihe Jing. Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1. Proc Natl Acad Sci USA. (2010) 107,18886-891.
  4. Yihua Sun, Yan Ren, Zhaoyuan Fang, Chenguang Li, Rong Fang, Bin Gao, Xiangkun Han, Weidong Tian, William Pao, Haiquan Chen, Hongbin Ji. Lung Adenocarcinoma From East Asian Never-Smokers Is a Disease Largely Defined by Targetable Oncogenic Mutant Kinases. J Clin Oncol. (2010) 28,4616-620.
  5. Fuming Li, Pingyu Liu, Changcheng Liu, Dao Xiang, Li Deng, Wenlin Li, Kirk J. Wangensteen, Jianguo Song, Yue Ma, Lijian Hui, Lixin Wei, Lingsong Li, Xiaoyan Ding, Yiping Hu, Zhiying He, Xin Wang. Hepatoblast-like progenitor cells derived from embryonic stem cells can repopulate livers of mice. Gastroenterology. (2010) 139,2158-169.e8.
  6. Haibo Wang, Bo Zhao, Yanqing Zhong, Kaicheng Li, Ziyan Li, Qiongwang, Yinjing Lu, Zhenning Zhang, Shaoqiu He, Hancheng Zheng, Shengxi Wu, Tomas G.M.H?kfelt, Lan Bao, Xu Zhang. Coexpression of δ- and μ-opioid receptors in nociceptive sensory neurons. Proc Natl Acad Sci U S A. (2010) 107,13117-122.
  7. Xiaowei Zhang, Xiaojing Yan, Ziren Zhou, Feifei Yang, Ziyu Wu, Hongbin Sun, Wenxue Liang, Aixin Song, Valérie Lallemand-Breitenbach, Marion Jeanne, Qunye Zhang, Huaiyu Yang, Qiuhua Huang, Guangbiao Zhou, Jianhua Tong, Yan Zhang, Jihui Wu, Hongyu Hu, Hugues de Thé, Saijuan Chen, Zhu Chen. Arsenic Trioxide Controls the Fate of the PML-RAR Oncoprotein by Directly Binding PML. Science. (2010) 328,240-243.
  8. Dan Du, Feilai Xu, Lihou Yu, Chenyi Zhang, Xuefeng Lu, Haixin Yuan, Qin Huang, Fan Zhang, Hongyan Bao, Lianghui Jia, Xunwei Wu, Xueliang Zhu, Xiaohui Zhang, Zhe Zhang, Zhengjun Chen. The Tight Junction Protein, Occludin, Regulates the Directional Migration of Epithelial Cells. Dev Cell. (2010) 18,52-63.
  9. Mingliang Zhang, Xiajing Tong, Xiaohong Fu, Bo O Zhou, Jianyong Wang, Xinhua Liao, Qianjin Li, Ning Shen, Jianping Ding, Jinqiu Zhou. Yeast telomerase subunit Est1p has guanine quadruplex–promoting activity that is required for telomere elongation. Nat Struct Mol Biol. (2010) 17,202-209.
  10. Xu Zhang, Lan Bao, Guoqiang Ma. Sorting of neuropeptides and neuropeptide receptors into secretory pathways. Prog Neurobiol. (2010) 90,276-283.
  11. Jialei Hu, Bo O.Zhou, Runrui Zhang, Kangling Zhang, Jinqiu Zhou, Guoliang Xu. The N-terminus of histone H3 is required for de novo DNA methylation in chromatin. Proc Natl Acad Sci USA. (2009) 106,22187-192.
  12. Rui Yue, Jiuhong Kang, Cong Zhao, Wenxiang Hu, Yawei Tang, Xiaosong Liu, Gang Pei. β-Arrestin1 Regulates Zebrafish Hematopoiesis through Binding to YY1 and Relieving Polycomb Group Repression. Cell. (2009) 139,535-546.
  13. Changsheng Du, Chang Liu, Jiuhong Kang, Guixian Zhao, Zhiqiang Ye, Shichao Huang, Zhenxin Li, Zhiying Wu, Gang Pei. MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol. (2009) 10,1252-259.
  14. Xinchao Pan, Xunde Wang, Weiwei Lei, Lihua Min, Yanan Yang, Xin Wang, Jianguo Song. Nitric oxide suppresses transforming growth factor-β1-induced epithelial-to-mesenchymal transition and apoptosis in mouse hepatocytes. Hepatology. (2009) 50,1577-587.
  15. Yihui Lin, Purvi M.Kakadia, Ying Chen, Yaqiang Li, Aniruddha J.Deshpande, Christian Buske, Kangling Zhang, Yi Zhang, Guoliang Xu, Stefan K.Bohlander. Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10–positive leukemias. Blood. (2009) 114,651-658.
  16. Xiaohui Zhang, Kenneth Halvorsen, Cheng-Zhong Zhang, Wesley P. Wong, Timothy A.Springer. Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor. Science. (2009) 324.1330-334.
  17. Yongli Shan, Lihou Yu, Yan Li, Youdong Pan, Qiangge Zhang, Fubin Wang, Jianfeng Chen, Xueliang Zhu. Nudel and FAK as Antagonizing Strength Modulators of Nascent Adhesions through Paxillin. PLoS Biol. (2009) 7,e1000116.
  18. Wei Wang, Lu Huang, Yan Huang, Jingwen Yin, Arnold J. Berk, Jeffrey M. Friedman, Gang Wang. Mediator MED23 Links Insulin Signaling to the Adipogenesis Transcription Cascade. Dev Cell. (2009) 16,764-771.
  19. Feilong Meng, Yan Hu, Ning Shen, Xiajing Tong, Jianyong Wang, Jianping Ding and Jinqiu Zhou. Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication. EMBO J. (2009) 28,1466-478.
  20. Sheng Li, Hao Wang, Baozhen Peng, Meilan Zhang, Daipong Zhang, Sheng Hou, Yajun Guo, Jianping Ding. Efalizumab binding to the LFA-1 αL I domain blocks ICAM-1 binding via steric hindrance. Proc Natl Acad Sci USA. (2009) 106,4349-354.
  21. Li Ma, Mingying Tsai, Shusheng Wang, Bingwen Lu, Rong Chen, John R.Yates III, Xueliang Zhu, Yixian Zheng. Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. Nat Cell Biol. (2009) 11,247-256.
  22. Haixin Yuan, Hong Zhang, Xunwei Wu, Zhe Zhang, Dan Du, Wenchao Zhou, Shuhua Zhou, Cord Brakebusch, Zhengjun Chen. Hepatocyte-Specific Deletion of Cdc42 Results in Delayed Liver Regeneration After Partial Hepatectomy in Mice. Hepatology. (2009) 49,240-249.
  23. Bing Luan, Jian Zhao, Haiya Wu, Baoyu Duan, Guangwen Shu, Xiaoying Wang, Dangsheng Li, Weiping Jia, Jiuhong Kang, Gang Pei. Deficiency of a β-arrestin-2 signal complex contributes to insulin resistance. Nature. (2009) 457,1146-149.
  24. Hong Tang, Liang Da, Yi Mao, Ying Li, Dong Li, Zhenhua Xu, Feng Li, Yifei Wang, Pierre Tiollais, Tsaiping Li, Mujun Zhao. Hepatitis B Virus X Protein Sensitizes Cells to Starvation-Induced Autophagy via Up-regulation of Beclin 1 Expression. Hepatology. (2009) 49,60-71.
  25. Jing Liao, Chun Cui, Siye Chen, Jiangtao Ren, Jijun Chen, Yuan Gao, Hui Li, Nannan Jia, Lu Cheng, Huasheng Xiao, Lei Xiao. Generation of Induced Pluripotent Stem Cell Lines from Adult Rat Cells. Cell Stem Cell. (2009) 4,11-15.
  26. Xiaoming Wang, Gang Xiao, Yafeng Zhang, Xiaomin Wen, Xiang Gao, Seiji Okada, Xiaolong Liu. Regulation of Tcrb recombination ordering by c-Fos-dependent RAG deposition. Nat Immunol. (2008) 9,794-801.
  27. Mude Shi, Weiwen Deng, Enguang Bi, Kairui Mao, Yongyong Ji, Guomei Lin, Xiaodong Wu, Zhiyun Tao, Zhenhu Li, Xinfen Cai, Shuhui Sun, Charlie Xiang, Bing Sun. TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation. Nat Immunol. (2008) 9,369-377.
  28. Mingcan Yu, Liuli Su, Lin Zou, Ye Liu, Na Wu, Ling Kong, Ziheng Zhuang, Lei Sun, Haipeng Liu, Junhao Hu, Dangsheng Li, Jack L Strominger, Jingwu Zang, Gang Pei, Baoxue Ge. An essential function for b-arrestin 2 in the inhibitory.signaling of natural killer cells. Nat Immunol. (2008) 9,898-907.
  29. Liang Ge, Jing Wang, Wei Qi, Honghua Miao, Jian Cao, Yuxiu Qu, Boliang Li, Baoliang Song. The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1. Cell Metab. (2008) 7,508-519.
  30. Wei Mo, Liang Zhang, Guohua Yang, Jianwei Zhai, Zhonghua Hu, Yuelei Chen, Xu Chen, Lijian Hui, Ruimin Huang, Gengxi Hu. Nuclear β-Arrestin1 Functions as a Scaffold for the Dephosphorylation of STAT1 and Moderates the Antiviral Activity of IFN-γ. Mol Cell. (2008) 31,695-707.
  31. Yidong Shen, Ning Li, Shuang Wu, Yizhuo Zhou, Yongli Shan, Qiangge Zhang, Chong Ding, Quan Yuan, Fukun Zhao, Rong Zeng, Xueliang Zhu. Nudel Binds Cdc42GAP to Modulate Cdc42 Activity at the Leading Edge of Migrating Cells. Dev Cell. (2008) 14,342-353.
  32. Weijun Pan, Sun-Cheol Choi, He Wang, Yuanbo Qin, Laura Volpicelli-Daley, Laura Swan, Louise Lucast, Cynthia Khoo, Xiaowu Zhang, Lin Li, Charles S.Abrams, Sergei Y.Sokol, Dianqing Wu. Wnt3a-Mediated Formation of Phosphatidylinositol 4,5-Bisphosphate Regulates LRP6 Phosphorylation. Science. (2008) 321,1350-353.
  33. Xiaoqing Gan, Jiyong Wang, Ying Xi, Zhili Wu, Yiping Li, Lin Li. Nuclear Dvl,c-Jun,β-catenin,and TCF form a complex leading to stabilization of β-catenin-TCF interaction. J Cell Biol. (2008) 180,1087-100.
  34. Yu Ding, Ying Xi, Ting Chen, Jiyong Wang, Donglei Tao, Zhili Wu, Yiping Li, Chen Li, Rong Zeng, Lin Li. Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation. J Cell Biol. (2008) 182,865-872.
  35. Haibo Wang, Jintao Wang, Lei Zhang, Zhen H Geng, Weili Xu, Tao Xu, Yuqing Huo, Xueliang Zhu, Edward F Plow, Ming Chen, Jianguo Geng. P-selectin primes leukocyte integrin activation during inflammation. Nat Immunol. (2007) 8,882-892.
  36. Yufeng Shi, Yan Feng, Jiuhong Kang, Chang Liu, Zhenxin Li, Dangsheng Li, Wei Cao, Ju Qiu, Zhengliang Guo, Enguang Bi, Lei Zang, Chuanzhen Lu, Jingwu Z Zhang, Gang Pei. Critical regulation of CD4+ T cell survival and autoimmunity by β-arrestin 1. Nat Immunol. (2007) 8,817-824.
  37. Jian Cao, Jiang Wang, Wei Qi, Honghua Miao, Jing Wang, Liang Ge, Russell A.DeBose Boyd, Jingjie Tang, Boliang Li, Baoliang Song. Ufd1 Is a Cofactor of gp78 and Plays a Key Role in Cholesterol Metabolism by Regulating the Stability of HMG-CoA Reductase. Cell Metab. (2007) 6,115-128.
  38. Ge Bai, Nengyin Sheng, Zhihui Xie, Wei Bian, Yoshifumi Yokota, Robert Benezra, Ryoichiro Kageyama, Francois Guillemot, Naihe Jing. Id Sustains Hes1 Expression to Inhibit Precocious Neurogenesis by Releasing Negative Autoregulation of Hes1. Dev Cell. (2007) 13,283-297.
  39. Lei Xiong, Fei Kou, Ying Yang, Jiarui Wu. A novel role for IGF-1R in p53-mediated apoptosis through translational modulation of the p53-Mdm2 feedback loop. J Cell Biol. (2007) 178,995-1007.
  40. Shaogang Sun, Yujie Tang, Xiwen Lou, Lianhui Zhu, Kai Yang, Bianhong Zhang, Hexin Shi, Chen Wang. UXT is a novel and essential cofactor in the NF-κB transcriptional enhanceosome. J Cell Biol. (2007) 178,231-244.
  41. Yang Xiang, Ziqi Zhu, Gang Han, Xiaolei Ye, Bo Xu, Zhouchun Peng, Yuanjun Ma, Yi Yu, Hanqing Lin, Adele Pin Chen, Charlie Degui Chen. JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer. Proc Natl Acad Sci USA. (2007) 104,19226-231.
  42. Yanxiang Ni, Xiaohui Zhao, Guobin Bao, Lin Zou, Lin Teng, Zhu Wang, Min Song, Jiaxiang Xiong, Yun Bai, Gang Pei. Activation of β2-adrenergic receptor stimulates γ-secretase activity and accelerates amyloid plaque formation. Nat Med. (2006) 12,1390-396.
  43. Yaya Wang, Yawei Tang, Lin Teng, Yalan Wu, Xiaohui Zhao, Gang Pei. Association of β-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat Immunol. (2006) 7,139-147.
  44. Quanhu Sheng, Lianshui Wang, Jie Dai, Xiaosheng Jiang, Rongxia Li, Danjun Ma,Yixue Li, Rong Zeng, Jiarui Wu. Comparison of a proteomic approach with a microarraybased approach to detect exons in the mouse genome. Nat Genet. (2006) 38,1223-224.
  45. Guanghua Huang, Huafeng Wang, Song Chou, Xinyi Nie, Jiangye Chen, Haoping Liu. Bistable expression of WOR1, a master regulator of white-opaque switching in Candida albicans. P Natl Acad Sci USA. (2006) 103,12813-818.
  46. Wei Lu, Bojian Zheng, Ke Xu, Wolfgang Schwarz, Jiadong Cheng, Shuming Duan, Vincent Deubel, Bing Sun. Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release. P Natl Acad Sci USA. (2006) 103,12540-545.
  47. Yiguo Wang, Dan Du, Longhou Fang, Guang Yang, Chenyi Zhang, Rong Zeng, Axel Ullrich, Friedrich Lottspeich, Zhengjun Chen. Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling. EMBO J. (2006) 5,5058-5070.
  48. Yuki Okada, Qin Feng, Yihui Lin, Qi Jiang, Yaqiang Li, Vernon M. Coffield, Lishan Su, Guoliang Xu, Yi Zhang. hDOT1L Links Histone Methylation to Leukemogenesis. Cell. (2005) 121,167-178.
  49. Jiuhong Kang, Yufeng Shi, Bin Xiang, Bin Qu, Wenjuan Su, Min Zhu, Min Zhang, Guobin Bao, Feifei Wang, Xiaoqing Zhang, Rongxi Yang, Fengjuan Fan, Gang Pei, Lan Ma. A Nuclear Function of b-Arrestin1 in GPCR Signaling: Regulation of Histone Acetylation and Gene Transcription. Cell. (2005) 123,833-847.
  50. Zhong Li, Xiemei Dong, Zhenglong Wang, Wenzhong Liu, Ning Deng, Yu Ding, Liuya Tang, Tim Hla, Rong Zeng, Lin Li, Dianqing Wu. Regulation of PTEN by Rho small GTPases. Nat Cell Biol. (2005) 7,399-407.
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